Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection

OBJECTIVE: To characterize cerebrospinal fluid (CSF) YKL-40, a unique biomarker that reflects activation of microglial cells, in acute (AHI) and chronic HIV-1 infection (CHI) and to determine the effect of treatment initiation on levels of this marker. DESIGN: Cross-sectional study of two groups of...

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Publicado no:AIDS
Main Authors: Peluso, Michael J., Valcour, Victor, Phanuphak, Nittaya, Ananworanich, Jintanat, Fletcsher, James LK, Chalermchai, Thep, Krebs, Shelly J., Robb, Merlin L., Hellmuth, Joanna, Gisslén, Magnus, Zetterberg, Henrik, Spudich, Serena
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844231/
https://ncbi.nlm.nih.gov/pubmed/27819802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001314
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