High Number of Activated CD8+ T Cells Targeting HIV Antigens are Present in Cerebrospinal Fluid in Acute HIV Infection

BACKGROUND: Central nervous system (CNS) infiltration by CD8+ T cells is associated with neuroinflammation in many neurodegenerative diseases, including HIV-associated dementia. However, the role of CD8+ T cells in the CNS during acute HIV infection is unknown. METHODS: We analyzed the phenotype, ge...

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Bibliografiset tiedot
Julkaisussa:J Acquir Immune Defic Syndr
Päätekijät: Kessing, Cari F., Spudich, Serena, Valcour, Victor, Cartwright, Pearline, Chalermchai, Thep, Fletcher, James L.K., Nichols, Carmen, Josey, Benjamin J., Slike, Bonnie, Krebs, Shelly J., Sailsuta, Napapon, Lerdlum, Sukalaya, Jagodzinski, Linda, Tipsuk, Somporn, Suttichom, Duanghathai, Rattanamanee, Somprartthana, Zetterberg, Henrik, Hellmuth, Joanna, Phanuphak, Nittaya, Robb, Merlin L., Michael, Nelson L., Ananworanich, Jintanat, Trautmann, Lydie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388590/
https://ncbi.nlm.nih.gov/pubmed/28177966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001301
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