High Number of Activated CD8+ T Cells Targeting HIV Antigens are Present in Cerebrospinal Fluid in Acute HIV Infection

BACKGROUND: Central nervous system (CNS) infiltration by CD8+ T cells is associated with neuroinflammation in many neurodegenerative diseases, including HIV-associated dementia. However, the role of CD8+ T cells in the CNS during acute HIV infection is unknown. METHODS: We analyzed the phenotype, ge...

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Publicado no:J Acquir Immune Defic Syndr
Main Authors: Kessing, Cari F., Spudich, Serena, Valcour, Victor, Cartwright, Pearline, Chalermchai, Thep, Fletcher, James L.K., Nichols, Carmen, Josey, Benjamin J., Slike, Bonnie, Krebs, Shelly J., Sailsuta, Napapon, Lerdlum, Sukalaya, Jagodzinski, Linda, Tipsuk, Somporn, Suttichom, Duanghathai, Rattanamanee, Somprartthana, Zetterberg, Henrik, Hellmuth, Joanna, Phanuphak, Nittaya, Robb, Merlin L., Michael, Nelson L., Ananworanich, Jintanat, Trautmann, Lydie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388590/
https://ncbi.nlm.nih.gov/pubmed/28177966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001301
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