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Genome Editing a Mouse Locus Encoding a Variant Histone, H3.3B, to Report on its Expression in Live Animals

Chromatin remodeling via incorporation of histone variants plays a key role in the regulation of embryonic development. The histone variant H3.3 has been associated with a number of early events including formation of the paternal pronucleus upon fertilization. The small number of amino acid differe...

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Detalhes bibliográficos
Publicado no:Genesis
Main Authors: Wen, Duancheng, Noh, Kyung-Min, Goldberg, Aaron D., Allis, C. David, Rosenwaks, Zev, Rafii, Shahin, Banaszynski, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844183/
https://ncbi.nlm.nih.gov/pubmed/25262655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22827
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