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Detection of PRMT1 inhibitors with stopped flow fluorescence
Protein arginine methyltransferases (PRMTs) are crucial epigenetic regulators in eukaryotic organisms that serve as histone writers for chromatin remodeling. PRMTs also methylate a variety of non-histone protein substrates to modulate their function and activity. The development of potent PRMT inhib...
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| Veröffentlicht in: | Signal Transduct Target Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843908/ https://ncbi.nlm.nih.gov/pubmed/29535867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-018-0009-6 |
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