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Preclinical validations of [(18)F]FPyPEGCBT-c(RGDfK): a (18)F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis
BACKGROUND: α(V)β(3), α(V)β(5) and α(5)β(1) integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they have been selected as promising therapeutic targets. Positron emission tomography (PET) is providing a unique non-...
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| Published in: | EJNMMI Radiopharm Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer International Publishing
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843817/ https://ncbi.nlm.nih.gov/pubmed/29564392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-016-0019-z |
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