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Preclinical validations of [(18)F]FPyPEGCBT-c(RGDfK): a (18)F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis

BACKGROUND: α(V)β(3), α(V)β(5) and α(5)β(1) integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to healthy tissues; thereby they have been selected as promising therapeutic targets. Positron emission tomography (PET) is providing a unique non-...

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Bibliografiske detaljer
Udgivet i:EJNMMI Radiopharm Chem
Main Authors: Colin, Didier J., Inkster, James A. H., Germain, Stéphane, Seimbille, Yann
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843817/
https://ncbi.nlm.nih.gov/pubmed/29564392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-016-0019-z
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