RTS,S malaria vaccine efficacy and immunogenicity during Plasmodium falciparum challenge is associated with HLA genotype

Although RTS,S remains the most advanced malaria vaccine, the factors influencing differences in vaccine immunogenicity or efficacy between individuals or populations are still poorly characterised. The analyses of genetic determinants of immunogenicity have previously been restricted by relatively...

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Vydáno v:Vaccine
Hlavní autoři: Nielsen, C.M., Vekemans, J., Lievens, M., Kester, K.E., Regules, J.A., Ockenhouse, C.F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843576/
https://ncbi.nlm.nih.gov/pubmed/29439870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.01.069
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