SMOOTH MUSCLE CELL MINERALOCORTICOID RECEPTOR AS A MEDIATOR OF CARDIOVASCULAR STIFFNESS WITH AGING

Stiffening of the vasculature with aging is a strong predictor of adverse cardiovascular events, independent of all other risk factors including blood pressure, yet no therapies target this process. Mineralocorticoid receptors in smooth muscle cells have been implicated in the regulation of vascular...

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Publié dans:Hypertension
Auteurs principaux: Kim, Seung Kyum, McCurley, Amy T., DuPont, Jennifer J., Aronovitz, Mark, Moss, M. Elizabeth, Stillman, Isaac E., Karumanchi, S. Ananth, Christou, Demetra D., Jaffe, Iris Z.
Format: Artigo
Langue:Inglês
Publié: 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843545/
https://ncbi.nlm.nih.gov/pubmed/29463624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10437
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