LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer

Papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC) are characterized by genomic rearrangements and point mutations in the proto-oncogene RET. Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a suppressor of various receptor tyrosine kinases, including RET. LRIG1...

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Xehetasun bibliografikoak
Argitaratua izan da:Int J Oncol
Egile Nagusiak: Lindquist, David, Alsina, Fernando C., Herdenberg, Carl, Larsson, Catharina, Höppener, Jo, Wang, Na, Paratcha, Gustavo, Tarján, Miklós, Tot, Tibor, Henriksson, Roger, Hedman, Håkan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: D.A. Spandidos 2018
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843404/
https://ncbi.nlm.nih.gov/pubmed/29436694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4273
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