Multiparameter Analysis of the “Off-Target Effects” of Dasatinib on Bone Homeostasis in Patients with Newly Diagnosed Chronic Myelogenous Leukemia

We assessed patients with chronic myelogenous leukemia for serum Ca, PO4, bone alkaline phosphatase, N-telopeptide, osteoprotegerin levels and trabecular bone (TBA) in bone marrow (BM) specimens before and after treatment with dasatinib. We identified a significant increase in TBA % in post-dasatini...

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Bibliographic Details
Published in:Clin Lymphoma Myeloma Leuk
Main Authors: Hoehn, Daniela, Cortes, Jorge E., Medeiros, L. Jeffrey, Jabbour, Elias J., Hidalgo, Juliana E., Kanagal-Shamanna, Rashmi, Bueso-Ramos, Carlos E.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843379/
https://ncbi.nlm.nih.gov/pubmed/27521332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clml.2016.02.027
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