Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development

Soluble epoxide hydrolase (sEH) inhibition is reported to elevate endogenous epoxyeicosatrienoic acids (EET’s), which are known to play an important role in neuroprotection by inhibiting oxidative stress and neuroinflammation. In the present study, PTUPB, a dual inhibitor of sEH and COX-2, has been...

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Bibliografiske detaljer
Udgivet i:J Pharm Biomed Anal
Main Authors: Lakkappa, Navya, Krishnamurthy, Praveen T., Yamjala, Karthik, Hwang, Sung Hee, Hammock, Bruce D., Babu, B.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843369/
https://ncbi.nlm.nih.gov/pubmed/29169114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2017.11.043
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