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Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS
A rapid, selective, and reliable LC-MS(n) method has been developed and validated for the isolation and structural characterization of the degradation product of darunavir (DRV). DRV, an HIV-1 protease inhibitor, was subjected to intrinsic oxidative stress conditions using 30% hydrogen peroxide and...
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| Pubblicato in: | Sci Pharm |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Austrian Journal of Pharmaceutical Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727738/ https://ncbi.nlm.nih.gov/pubmed/26839843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1505-10 |
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