Integrating genome-wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin-Beck disease and primary osteoarthritis

BACKGROUND: Kashin-Beck disease (KBD) is an endemic osteochondropathy of unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar clinical manifestations and pathological changes to articular cartilage with KBD. METHODS: A genome-wide DNA methylation profile of a...

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Bibliografiska uppgifter
I publikationen:Arthritis Res Ther
Huvudupphovsmän: Wen, Yan, Li, Ping, Hao, Jingcan, Duan, Chen, Han, Jing, He, Awen, Du, Yanan, Liu, Li, Liang, Xiao, Zhang, Feng, Guo, Xiong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842623/
https://ncbi.nlm.nih.gov/pubmed/29514696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1531-1
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