Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease

Kashin-Beck disease (KBD) is a chronic osteochondropathy. The pathogenesis of growth and development failure of hand of KBD remains elusive now. In this study, we conducted a two-stage genome-wide association study (GWAS) of palmar length-width ratio (LWR) of KBD, totally including 493 study subject...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hao, Jingcan, Wang, Wenyu, Wen, Yan, Xiao, Xiao, He, Awen, Wu, Cuiyan, Wang, Sen, Guo, Xiong, Zhang, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216336/
https://ncbi.nlm.nih.gov/pubmed/28059113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40020
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