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Synthesis and cytotoxic evaluation of some novel quinoxalinedione diarylamide sorafenib analogues
A series of novel sorafenib analogues containing a quinoxalinedione ring and amide linker were synthesized. A total of 9 novel compounds in 6 synthetic steps were synthesized. Briefly, the amino group of p-aminophenol was first protected which then followed by O-arylation with 5-chloro-2-nitroanilin...
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| Publié dans: | Res Pharm Sci |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Medknow Publications & Media Pvt Ltd
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842488/ https://ncbi.nlm.nih.gov/pubmed/29606971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.223802 |
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