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Synthesis and cytotoxic evaluation of some novel quinoxalinedione diarylamide sorafenib analogues

A series of novel sorafenib analogues containing a quinoxalinedione ring and amide linker were synthesized. A total of 9 novel compounds in 6 synthetic steps were synthesized. Briefly, the amino group of p-aminophenol was first protected which then followed by O-arylation with 5-chloro-2-nitroanilin...

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Bibliografische gegevens
Gepubliceerd in:Res Pharm Sci
Hoofdauteurs: Khandan, Mojtaba, Sadeghian-Rizi, Sedighe, Khodarahmi, Ghadamali, Hassanzadeh, Farshid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Medknow Publications & Media Pvt Ltd 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842488/
https://ncbi.nlm.nih.gov/pubmed/29606971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.223802
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