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Silencing of syndecan-binding protein enhances the inhibitory effect of tamoxifen and increases cellular sensitivity to estrogen

OBJECTIVE: Tamoxifen is used as a complementary treatment for estrogen receptor (ER)-positive breast cancer (BCa), but many patients developed resistance. The aim of this study was to examine the role of syndecan-binding protein (SDCBP) silencing in ER-positive BCa cells. METHODS: In MCF-7/T47D cell...

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Publicado en:Cancer Biol Med
Main Authors: Zhang, Jun, Qian, Xiaolong, Liu, Fangfang, Guo, Xiaojing, Gu, Feng, Fu, Li
Formato: Artigo
Idioma:Inglês
Publicado: Chinese Anti-Cancer Association 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842332/
https://ncbi.nlm.nih.gov/pubmed/29545966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20892/j.issn.2095-3941.2017.0122
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