let-7 MicroRNAs Induce Tamoxifen Sensitivity by Downregulation of Estrogen Receptor α Signaling in Breast Cancer

MicroRNAs (miRNAs) play an important regulatory role in breast tumorigenesis. Previously, we found that let-7 miRNAs were downregulated significantly in formalin-fixed paraffin-embedded (FFPE) breast cancer tissues. In this study, we further found that endogenous levels of let-7b and let-7i miRNAs a...

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Detalhes bibliográficos
Main Authors: Zhao, Yingchun, Deng, Caishu, Lu, Weida, Xiao, Jing, Ma, Danjun, Guo, Mingxi, Recker, Robert R, Gatalica, Zoran, Wang, Zhaoyi, Xiao, Gary Guishan
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321804/
https://ncbi.nlm.nih.gov/pubmed/21826373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00225
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