Rap1 deficiency-provoked paracrine dysfunction impairs immunosuppressive potency of mesenchymal stem cells in allograft rejection of heart transplantation

Immunomodulatory activity of mesenchymal stem cells (MSCs) is largely mediated by paracrine factors. Our previous studies showed that activation of nuclear factor-kappa B (NF-κB) regulates cytokine/growth factor secretion by MSCs. This study aimed to elucidate the role of Rap1 (repressor/activator p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ding, Yue, Liang, Xiaoting, Zhang, Yuelin, Yi, Li, Shum, Ho Cheung, Chen, Qiulan, Chan, Barbara P., Fan, Huimin, Liu, Zhongmin, Tergaonkar, Vinay, Qi, Zhongquan, Tse, Hung-fat, Lian, Qizhou
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842217/
https://ncbi.nlm.nih.gov/pubmed/29515165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0414-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados