Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinomas (PDAs) are desmoplastic and can undergo epithelial-to-mesenchymal transition to confer metastasis and chemoresistance. Studies have demonstrated that phenotypically and functionally distinct stromal cell populations exist in PDAs. Fibroblast activation protein–expre...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Lo, Albert, Li, Chung-Pin, Buza, Elizabeth L., Blomberg, Rachel, Govindaraju, Priya, Avery, Diana, Monslow, James, Hsiao, Michael, Puré, Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841864/
https://ncbi.nlm.nih.gov/pubmed/28978805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92232
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