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A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism

The capacity of the liver to convert the metabolic input received from the incoming portal and arterial blood into the metabolic output of the outgoing venous blood has three major determinants: The intra-hepatic blood flow, the transport of metabolites between blood vessels (sinusoids) and hepatocy...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Berndt, Nikolaus, Horger, Marius Stefan, Bulik, Sascha, Holzhütter, Hermann-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841820/
https://ncbi.nlm.nih.gov/pubmed/29447152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006005
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