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Microenvironmental cues enhance mesenchymal stem cell-mediated immunomodulation and regulatory T-cell expansion

Mesenchymal stem cells (MSCs) are known to both have powerful immunosuppressive properties and promote allograft tolerance. Determining the environmental oxygen tension and inflammatory conditions under which MSCs are optimally primed for this immunosuppressive function is essential to their utiliza...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kadle, Rohini L., Abdou, Salma A., Villarreal-Ponce, Alvaro P., Soares, Marc A., Sultan, Darren L., David, Joshua A., Massie, Jonathan, Rifkin, William J., Rabbani, Piul, Ceradini, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841747/
https://ncbi.nlm.nih.gov/pubmed/29513756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193178
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