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Microenvironmental cues enhance mesenchymal stem cell-mediated immunomodulation and regulatory T-cell expansion

Mesenchymal stem cells (MSCs) are known to both have powerful immunosuppressive properties and promote allograft tolerance. Determining the environmental oxygen tension and inflammatory conditions under which MSCs are optimally primed for this immunosuppressive function is essential to their utiliza...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Kadle, Rohini L., Abdou, Salma A., Villarreal-Ponce, Alvaro P., Soares, Marc A., Sultan, Darren L., David, Joshua A., Massie, Jonathan, Rifkin, William J., Rabbani, Piul, Ceradini, Daniel J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841747/
https://ncbi.nlm.nih.gov/pubmed/29513756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193178
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