Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow – A proof of concept study

Diagnostic and prognostic evaluation of chronic lymphocytic leukemia (CLL) involves blood cell counts, immunophenotyping, IgVH mutation status, and cytogenetic analyses. We generated B-cell associated gene-signatures (BAGS) based on six naturally occurring B-cell subsets within normal bone marrow. O...

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Vydáno v:PLoS One
Hlavní autoři: Nørgaard, Caroline Holm, Jakobsen, Lasse Hjort, Gentles, Andrew J., Dybkær, Karen, El-Galaly, Tarec Christoffer, Bødker, Julie Støve, Schmitz, Alexander, Johansen, Preben, Herold, Tobias, Spiekermann, Karsten, Brown, Jennifer R., Klitgaard, Josephine L., Johnsen, Hans Erik, Bøgsted, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841735/
https://ncbi.nlm.nih.gov/pubmed/29513759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193249
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