Risk and treatment effect heterogeneity: re-analysis of individual participant data from 32 large clinical trials

Background: Risk of the outcome is a mathematical determinant of the absolute treatment benefit of an intervention, yet this can vary substantially within a trial population, complicating the interpretation of trial results. Methods: We developed risk models using Cox or logistic regression on a set...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Epidemiol
Hauptverfasser: Kent, David M, Nelson, Jason, Dahabreh, Issa J, Rothwell, Peter M, Altman, Douglas G, Hayward, Rodney A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Methodological Insights
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841614/
https://ncbi.nlm.nih.gov/pubmed/27375287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw118
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