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Using internally developed risk models to assess heterogeneity in treatment effects in clinical trials

BACKGROUND: Recent proposals suggest that risk-stratified analyses of clinical trials be routinely performed to better enable tailoring of treatment decisions to individuals. Trial data can be stratified using externally developed risk models (e.g. Framingham risk score), but such models are not alw...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Burke, James F, Hayward, Rodney A, Nelson, Jason P, Kent, David M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957096/
https://ncbi.nlm.nih.gov/pubmed/24425710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCOUTCOMES.113.000497
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