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Hypoxia and the prolylhydroxylase inhibitor FG-4592 protect corneal endothelial cells from mechanical and perioperative surgical stress

PURPOSE: Determine if hypoxia preconditioning can protect corneal endothelial cells from mechanical stress and perioperative procedures mimicking Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Preconditioning was delivered by 2 hours of 0.5% oxygen incubation in a hypoxia ch...

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Detalhes bibliográficos
Publicado no:Cornea
Principais autores: Bhadange, Yogesh, Lautert, Jeferson, Li, Shimin, Lawando, Edward, Kim, Edward T., Soper, Mark C., Price, Francis W., Price, Marianne O., Bonanno, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841548/
https://ncbi.nlm.nih.gov/pubmed/29504956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000001430
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