Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients

Safety concerns with erythropoietin analogues and intravenous (IV) iron for treatment of anemia in CKD necessitate development of safer therapies. Roxadustat (FG-4592) is an orally bioavailable hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor that promotes coordinated erythropoiesis throu...

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Podrobná bibliografie
Vydáno v:J Am Soc Nephrol
Hlavní autoři: Besarab, Anatole, Chernyavskaya, Elena, Motylev, Igor, Shutov, Evgeny, Kumbar, Lalathaksha M., Gurevich, Konstantin, Chan, Daniel Tak Mao, Leong, Robert, Poole, Lona, Zhong, Ming, Saikali, Khalil G., Franco, Marietta, Hemmerich, Stefan, Yu, Kin-Hung Peony, Neff, Thomas B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Clinical Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814189/
https://ncbi.nlm.nih.gov/pubmed/26494833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015030241
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