Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of...

Por Seeley, Todd W, Sternlicht, Mark D, Klaus, Stephen J, Neff, Thomas B, Liu, David Y
Publicado no Hypoxia (Auckl) (2017)

Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patients

Por Besarab, Anatole, Provenzano, Robert, Hertel, Joachim, Zabaneh, Raja, Klaus, Stephen J., Lee, Tyson, Leong, Robert, Hemmerich, Stefan, Yu, Kin-Hung Peony, Neff, Thomas B.
Publicado no Nephrol Dial Transplant (2015)

Phase 1 Study of Anti-CTGF Monoclonal Antibody in Patients with Diabetes and Microalbuminuria

Por Adler, Sharon G., Schwartz, Sherwyn, Williams, Mark E., Arauz-Pacheco, Carlos, Bolton, Warren K., Lee, Tyson, Li, Dongxia, Neff, Thomas B., Urquilla, Pedro R., Sewell, K. Lea
Publicado em 2010

Roxadustat (FG-4592): Correction of Anemia in Incident Dialysis Patients

Por Besarab, Anatole, Chernyavskaya, Elena, Motylev, Igor, Shutov, Evgeny, Kumbar, Lalathaksha M., Gurevich, Konstantin, Chan, Daniel Tak Mao, Leong, Robert, Poole, Lona, Zhong, Ming, Saikali, Khalil G., Franco, Marietta, Hemmerich, Stefan, Yu, Kin-Hung Peony, Neff, Thomas B.
Publicado no J Am Soc Nephrol (2016)

Oral Hypoxia–Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment of Anemia in Patients with CKD

Por Provenzano, Robert, Besarab, Anatole, Sun, Chao H., Diamond, Susan A., Durham, John H., Cangiano, Jose L., Aiello, Joseph R., Novak, James E., Lee, Tyson, Leong, Robert, Roberts, Brian K., Saikali, Khalil G., Hemmerich, Stefan, Szczech, Lynda A., Yu, Kin-Hung Peony, Neff, Thomas B.
Publicado no Clin J Am Soc Nephrol (2016)

Phase 2 studies of oral hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 for treatment of anemia in China

Por Chen, Nan, Qian, Jiaqi, Chen, Jianghua, Yu, Xueqing, Mei, Changlin, Hao, Chuanming, Jiang, Gengru, Lin, Hongli, Zhang, Xinzhou, Zuo, Li, He, Qiang, Fu, Ping, Li, Xuemei, Ni, Dalvin, Hemmerich, Stefan, Liu, Cameron, Szczech, Lynda, Besarab, Anatole, Neff, Thomas B., Peony Yu, Kin-Hung, Valone, Frank H.
Publicado no Nephrol Dial Transplant (2017)