2-aminopurine suppresses the TGF-β1-induced epithelial–mesenchymal transition and attenuates bleomycin-induced pulmonary fibrosis

The epithelial–mesenchymal transition (EMT) is a multifunctional cell process involved in the pathogenesis of numerous conditions, including fibrosis and cancer. Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease characterized by fibroblast accumulation and collagen deposition in...

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Vydáno v:Cell Death Discov
Hlavní autoři: Weng, Dong, Chen, Jian-xia, Li, Hao-hao, Liu, Feng, Zhou, Li-dan, Liu, Hai-peng, Zheng, Rui-juan, Jiang, Yan, Liu, Zhong-hua, Ge, Baoxue
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841362/
https://ncbi.nlm.nih.gov/pubmed/29531814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0016-3
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