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SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling

Osteopontin (OPN) is a promoter for tumor progression. It has been reported to promote non-small cell lung cancer (NSCLC) progression via the activation of nuclear factor-κB (NF-κB) signaling. As the increased acetylation of NF-κB p65 is linked to NF-κB activation, the regulation of NF-κB p65 acetyl...

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Publicat a:Onco Targets Ther
Autors principals: Li, Xuejiao, Jiang, Zhongxiu, Li, Xiangmin, Zhang, Xiaoye
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841350/
https://ncbi.nlm.nih.gov/pubmed/29535539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S137146
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