Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression

Cancer stem cells (CSCs) niche in the tumor microenvironment is responsible for cancer recurrence and therapy failure. To better understand its molecular and biological involvement in hepatocellular carcinoma (HCC) progression, one can design more effective therapies and tailored then to individual...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Rani, Bhavna, Malfettone, Andrea, Dituri, Francesco, Soukupova, Jitka, Lupo, Luigi, Mancarella, Serena, Fabregat, Isabel, Giannelli, Gianluigi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841307/
https://ncbi.nlm.nih.gov/pubmed/29515105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0384-5
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