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Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression

Cancer stem cells (CSCs) niche in the tumor microenvironment is responsible for cancer recurrence and therapy failure. To better understand its molecular and biological involvement in hepatocellular carcinoma (HCC) progression, one can design more effective therapies and tailored then to individual...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Rani, Bhavna, Malfettone, Andrea, Dituri, Francesco, Soukupova, Jitka, Lupo, Luigi, Mancarella, Serena, Fabregat, Isabel, Giannelli, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841307/
https://ncbi.nlm.nih.gov/pubmed/29515105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0384-5
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