Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

Kidney function is directly linked to the number of nephrons which are generated until 32–36 weeks gestation in humans. Failure to make nephrons during development leads to congenital renal malformations, whilst nephron loss in adulthood occurs in progressive renal disease. Therefore, an understandi...

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Udgivet i:Cell Death Discov
Main Authors: Price, Karen L., Kolatsi-Joannou, Maria, Mari, Chiara, Long, David A., Winyard, Paul J. D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841285/
https://ncbi.nlm.nih.gov/pubmed/29531810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0021-6
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