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A Positive Role of Cadherin in Wnt/β-Catenin Signalling during Epithelial-Mesenchymal Transition

The Wnt/β-catenin signalling pathway shares a key component, β-catenin, with the cadherin-based adhesion system. The signalling function of β-catenin is conferred by a soluble cytoplasmic pool that is unstable in the absence of a Wnt signal, whilst the adhesion function is based on a cadherin-bound,...

詳細記述

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書誌詳細
主要な著者: Howard, Sara, Deroo, Tom, Fujita, Yasuyuki, Itasaki, Nobue
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166074/
https://ncbi.nlm.nih.gov/pubmed/21909376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023899
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