Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation

Invasive pulmonary disease due to the mold Aspergillus fumigatus can be life-threatening in lung transplant recipients, but the risk factors remain poorly understood. To study this process, we used a tracheal allograft mouse model that recapitulates large airway changes observed in patients undergoi...

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發表在:Sci Transl Med
Main Authors: Hsu, Joe L., Manouvakhova, Olga V., Clemons, Karl V., Inayathullah, Mohammed, Tu, Allen B., Sobel, Raymond A., Tian, Amy, Nazik, Hasan, Pothineni, Venkata R., Pasupneti, Shravani, Jiang, Xinguo, Dhillon, Gundeep S., Bedi, Harmeet, Rajadas, Jayakumar, Haas, Hubertus, Aurelian, Laure, Stevens, David A., Nicolls, Mark R.
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841257/
https://ncbi.nlm.nih.gov/pubmed/29467298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aag2616
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