Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation

Invasive pulmonary disease due to the mold Aspergillus fumigatus can be life-threatening in lung transplant recipients, but the risk factors remain poorly understood. To study this process, we used a tracheal allograft mouse model that recapitulates large airway changes observed in patients undergoi...

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Publicado en:Sci Transl Med
Autores principales: Hsu, Joe L., Manouvakhova, Olga V., Clemons, Karl V., Inayathullah, Mohammed, Tu, Allen B., Sobel, Raymond A., Tian, Amy, Nazik, Hasan, Pothineni, Venkata R., Pasupneti, Shravani, Jiang, Xinguo, Dhillon, Gundeep S., Bedi, Harmeet, Rajadas, Jayakumar, Haas, Hubertus, Aurelian, Laure, Stevens, David A., Nicolls, Mark R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841257/
https://ncbi.nlm.nih.gov/pubmed/29467298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aag2616
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