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ROLE OF CYTOCHROME P450S IN THE GENERATION AND METABOLISM OF REACTIVE OXYGEN SPECIES

The cytochrome P450 (CYP) enzymes are a diverse group of heme monooxygenases that, through the course of their reaction cycle, contribute to cellular reactive oxygen species (ROS). CYP enzymes play a crucial role in human physiology and are involved in drug and xenobiotic metabolism as well as biosy...

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Détails bibliographiques
Publié dans:Curr Opin Toxicol
Auteurs principaux: Veith, Alex, Moorthy, Bhagavatula
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841237/
https://ncbi.nlm.nih.gov/pubmed/29527583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2017.10.003
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