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Enhanced percutaneous absorption of cilostazol nanocrystals using aqueous gel patch systems and clarification of the absorption mechanism

Cilostazol (CLZ), an anti-platelet agent, is primarily used following the onset of cerebral infarction. However, as CLZ is only marginally soluble in water, a strategy for patients with serious secondary conditions, such as impaired consciousness or aphagia, is required. In the present study, topica...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Ther Med
Prif Awduron: Yoshioka, Chiaki, Ito, Yoshimasa, Nagai, Noriaki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840931/
https://ncbi.nlm.nih.gov/pubmed/29545875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.5820
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