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Enhanced percutaneous absorption of cilostazol nanocrystals using aqueous gel patch systems and clarification of the absorption mechanism

Cilostazol (CLZ), an anti-platelet agent, is primarily used following the onset of cerebral infarction. However, as CLZ is only marginally soluble in water, a strategy for patients with serious secondary conditions, such as impaired consciousness or aphagia, is required. In the present study, topica...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Yoshioka, Chiaki, Ito, Yoshimasa, Nagai, Noriaki
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840931/
https://ncbi.nlm.nih.gov/pubmed/29545875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.5820
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