Pirfenidone Accelerates Wound Healing in Chronic Diabetic Foot Ulcers: A Randomized, Double-Blind Controlled Trial

BACKGROUND: Diabetic foot ulcers are one disabling complication of diabetes mellitus. Pirfenidone (PFD) is a potent modulator of extracellular matrix. Modified diallyl disulfide oxide (M-DDO) is an antimicrobial and antiseptic agent. AIM: To evaluate efficacy of topical PFD + M-DDO in a randomized,...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Gasca-Lozano, Luz E., Lucano-Landeros, Silvia, Ruiz-Mercado, Héctor, Salazar-Montes, Adriana, Sandoval-Rodríguez, Ana, Garcia-Bañuelos, Jesus, Santos-Garcia, Arturo, Davila-Rodriguez, Judith R., Navarro-Partida, José, Bojórquez-Sepúlveda, Hiram, Castañeda-Gomez, Juan, Domínguez-Rosales, José, Ruiz-Arcos, Myriam A., Sánchez-Parada, María Guadalupe, Armendariz-Borunda, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840678/
https://ncbi.nlm.nih.gov/pubmed/29675430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/3159798
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