Silencing LDHA inhibits proliferation, induces apoptosis and increases chemosensitivity to temozolomide in glioma cells

Glioblastoma multiforme (GBM) is a prevalent and aggressive disease, and the development of a novel therapy to better treat advanced GBM is urgently required. Lactate dehydrogenase A (LDHA), which functions as a key enzyme in transforming pyruvate into lactate, has attracted more attention in recent...

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Publicat a:Oncol Lett
Autors principals: Di, Hui, Zhang, Xinting, Guo, Yi, Shi, Yanfang, Fang, Chuan, Yuan, Yu, Wang, Jiwei, Shang, Chao, Guo, Wenzhe, Li, Chunhui
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840669/
https://ncbi.nlm.nih.gov/pubmed/29552147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.7932
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