Salivary glands regenerate after radiation injury through SOX2‐mediated secretory cell replacement

Salivary gland acinar cells are routinely destroyed during radiation treatment for head and neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential regenerative strategy for replacing injured tissue is the reactivation of endogenous stem cells by targeted therapeutic...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Emmerson, Elaine, May, Alison J, Berthoin, Lionel, Cruz‐Pacheco, Noel, Nathan, Sara, Mattingly, Aaron J, Chang, Jolie L, Ryan, William R, Tward, Aaron D, Knox, Sarah M
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840548/
https://ncbi.nlm.nih.gov/pubmed/29335337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708051
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