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SOX2 regulates acinar cell development in the salivary gland

Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gland, we demonstrate an unexpected role for SOX2 and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Emmerson, Elaine, May, Alison J, Nathan, Sara, Cruz-Pacheco, Noel, Lizama, Carlos O, Maliskova, Lenka, Zovein, Ann C, Shen, Yin, Muench, Marcus O, Knox, Sarah M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498133/
https://ncbi.nlm.nih.gov/pubmed/28623666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26620
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