SOX2 regulates acinar cell development in the salivary gland

Acinar cells play an essential role in the secretory function of exocrine organs. Despite this requirement, how acinar cells are generated during organogenesis is unclear. Using the acini-ductal network of the developing human and murine salivary gland, we demonstrate an unexpected role for SOX2 and...

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Pubblicato in:eLife
Autori principali: Emmerson, Elaine, May, Alison J, Nathan, Sara, Cruz-Pacheco, Noel, Lizama, Carlos O, Maliskova, Lenka, Zovein, Ann C, Shen, Yin, Muench, Marcus O, Knox, Sarah M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Developmental Biology and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498133/
https://ncbi.nlm.nih.gov/pubmed/28623666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26620
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