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MiR34 inhibition induces human heart progenitor proliferation

MiR34 involvement in myocardial injury repair and ageing has been well documented in mouse model. Our aim was to establish whether the inhibition of miR34 expression through locked nucleic acid (LNA) could be used as a pharmacological intervention to enhance human heart repair. Cardiac progenitor ce...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Iannolo, Gioacchin, Sciuto, Maria Rita, Raffa, Giuseppe Maria, Pilato, Michele, Conaldi, Pier Giulio
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840309/
https://ncbi.nlm.nih.gov/pubmed/29511160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0400-9
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