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Dual role for miR-34a in the control of early progenitor proliferation and commitment in the mammary gland and in breast cancer
The role of the tumour-suppressor miR-34 family in breast physiology and in mammary stem cells (MaSCs) is largely unknown. Here, we revealed that miR-34 family, and miR-34a in particular, is implicated in mammary epithelium homoeostasis. Expression of miR-34a occurs upon luminal commitment and diffe...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336680/ https://ncbi.nlm.nih.gov/pubmed/30093634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0445-3 |
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