Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons

The cellular prion protein, encoded by the gene Prnp, has been reported to be a receptor of β-amyloid. Their interaction is mandatory for neurotoxic effects of β-amyloid oligomers. In this study, we aimed to explore whether the cellular prion protein participates in the spreading of α-synuclein. Res...

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Udgivet i:Mol Neurobiol
Main Authors: Urrea, Laura, Segura-Feliu, Miriam, Masuda-Suzukake, Masami, Hervera, Arnau, Pedraz, Lucas, García Aznar, José Manuel, Vila, Miquel, Samitier, Josep, Torrents, Eduard, Ferrer, Isidro, Gavín, Rosalina, Hagesawa, Masato, del Río, José Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840251/
https://ncbi.nlm.nih.gov/pubmed/28229331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0451-4
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