Autoantibodies May Predict Immune-Related Toxicity: Results from a Phase I Study of Intralesional Bacillus Calmette–Guérin followed by Ipilimumab in Patients with Advanced Metastatic Melanoma

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced melanoma. The first ICI to demonstrate clinical benefit, ipilimumab, targets cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4); however, the long-term overall survival is just 22%. More than 40 years ago intralesion...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Immunol
Main Authors: Da Gama Duarte, Jessica, Parakh, Sagun, Andrews, Miles C., Woods, Katherine, Pasam, Anupama, Tutuka, Candani, Ostrouska, Simone, Blackburn, Jonathan M., Behren, Andreas, Cebon, Jonathan
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018
נושאים:
Immunology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840202/
https://ncbi.nlm.nih.gov/pubmed/29552014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00411
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