Remodeling the specificity of an endosomal CORVET tether underlies formation of regulated secretory vesicles in the ciliate Tetrahymena thermophila

In the endocytic pathway of animals, two related complexes, called CORVET (Class C Core Vacuole/Endosome Transport) and HOPS (Homotypic fusion and protein sorting), act as both tethers and fusion factors for early and late endosomes, respectively. Mutations in CORVET or HOPS lead to trafficking defe...

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Pubblicato in:Curr Biol
Autori principali: Sparvoli, Daniela, Richardson, Elisabeth, Osakada, Hiroko, Lan, Xun, Iwamoto, Masaaki, Bowman, Grant R., Kontur, Cassandra, Bourland, William A., Lynn, Denis H., Pritchard, Jonathan K., Haraguchi, Tokuko, Dacks, Joel B., Turkewitz, Aaron P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840023/
https://ncbi.nlm.nih.gov/pubmed/29478853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.01.047
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