Remodeling the specificity of an endosomal CORVET tether underlies formation of regulated secretory vesicles in the ciliate Tetrahymena thermophila

In the endocytic pathway of animals, two related complexes, called CORVET (Class C Core Vacuole/Endosome Transport) and HOPS (Homotypic fusion and protein sorting), act as both tethers and fusion factors for early and late endosomes, respectively. Mutations in CORVET or HOPS lead to trafficking defe...

Full description

Saved in:
Bibliographic Details
Published in:Curr Biol
Main Authors: Sparvoli, Daniela, Richardson, Elisabeth, Osakada, Hiroko, Lan, Xun, Iwamoto, Masaaki, Bowman, Grant R., Kontur, Cassandra, Bourland, William A., Lynn, Denis H., Pritchard, Jonathan K., Haraguchi, Tokuko, Dacks, Joel B., Turkewitz, Aaron P.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840023/
https://ncbi.nlm.nih.gov/pubmed/29478853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.01.047
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items